Coronavirus Breaking News

The coronavirus disease COVID-19 is currently reaching pandemic levels in various countries.

Oct 24, 2020 • 12:49 pm CDT

Fujifilm Holdings Corp. announced on October 22, 2020, that it has partnered with Shanghai-based Carelink Pharmaceutical Co. to seek approval in China for the antiviral medication Avigan to treat both COVID-19 and influenza.

Avigan selectively inhibits RNA polymerase necessary for influenza virus replication. Due to this mechanism of action, it has been expected that Avigan may have an antiviral effect on the novel coronavirus SARS-CoV-2, as they are RNA viruses of the same type as influenza viruses.

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Oct 24, 2020 • 12:34 pm CDT

Over 9,000 long-term care facilities have opted into the US government's pharmacy vaccination program since it was announced, Paul Mango, deputy chief of staff at HHS, told CNBC reporters on October 23, 2020. The US Department of Health and Human Services recently announced an agreement with the CVS and Walgreens pharmacy chains to administer vaccines to the elderly at long-term care and assisted living facilities, free of charge.

Previously, the National Community Pharmacists Association announced on August 31, 2020, that 86% of community pharmacists say they plan to offer the COVID-19 vaccines when they become available.

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Oct 24, 2020 • 10:29 am CDT

New Jersey-based Johnson & Johnson announced on October 23, 2020, that it is preparing to resume recruitment in the pivotal Phase 3 ENSEMBLE trial of its investigational Janssen COVID-19 vaccine Ad5-nCoV in the USA after a temporary pause. 'After a thorough evaluation of a serious medical event experienced by one study participant, no clear cause has been identified,' said the company's press statement.

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Oct 24, 2020 • 9:04 am CDT

Vancouver based Precision Nanosystems, Inc. (PNI) announced that it has received a commitment of up to $18.2 million in support from the Government of Canada under the Innovation, Science and Economic Development’s Strategic Innovation Fund to develop a COVID-19 vaccine. PNI stated on October 23, 2020, 'it will use the investment to advance a best-in-class COVID-19 mRNA vaccine candidate to clinical trials.'

The Government of Canada has now signed vaccine supply agreements with Medicago, AstraZeneca, Sanofi and GlaxoSmithKline, Johnson & Johnson, Novavax, Pfizer, and Moderna. Agreements signed to date will secure access to up to 358 million doses of their different COVID-19 vaccine candidates.

Oct 23, 2020 • 4:38 pm CDT

New questions are at the forefront as a study from (9) children's hospitals published in the Journal of Clinical Microbiology on October 22, 2020, finds that most asymptomatic children who tested positive for COVID-19 had relatively low levels of the SARS-CoV-2 virus, compared to symptomatic children.

First author Larry Kociolek, M.D., pediatric infectious diseases expert at Ann & Robert H. Lurie Children's Hospital of Chicago and Assistant Professor of Pediatrics at Northwestern University, stated in a press release: "At this stage, we can't predict which children are likely to carry more or less virus, because, in every age group we tested, there were some asymptomatic kids with a higher viral load."

"However, even the groups of asymptomatic kids with the highest viral load in our study still had lower viral loads than children with symptoms."

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Oct 23, 2020 • 4:28 pm CDT

Just one flight into the country of Ireland led to a 59-person outbreak, reported a new study in Eurosurveillance, which was published on October 22, 2020. Diagnostic tests eventually confirmed that 13 (26.5%) of the original 49 passengers on-board this flight were positive for the SARS-CoV-2 coronavirus, with the other 46 individuals infected with the virus by a passenger.

These researchers suggest 'Stringent on-board infection prevention and control measures are vital to reduce the risk of both symptomatic and asymptomatic in-flight coronavirus transmission.'

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Oct 23, 2020 • 3:32 pm CDT

The Massachusetts Department of Public Health (MDPH) issued a new public health order on October 22, 2020, prohibiting indoor ice rinks and ice skating facilities from operating from October 23, 2020, to November 7, 2020. This pause will allow for the development of stronger COVID-19 protocols to further protect players, families, coaches, arena staff, and other participants, as well as communities surrounding hockey rinks.

As of October 23rd, MDPH has not reported any COVID-19 fatalities related to ice skating activities.

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Oct 23, 2020 • 2:16 pm CDT

According to a research letter published in the Journal of the American Medical Association on October 12, 2020, the COVID-19 pandemic caused just two-thirds of the excess fatalities during the first 5-months of the outbreak in the USA.

The balance of the excess fatalities was related to the indirect effects of the disease on older Americans suffering from dementia and Alzheimer’s disease.

Mortality rates for Alzheimer's disease/dementia increased twice, between weeks ending March 21 and April 11, 2020, and between weeks ending June 6 and July 25, 2020, the latter coinciding with the summer surge of SARS-CoV-2 cases in sunbelt states of the USA.

Oct 23, 2020 • 1:45 pm CDT

Nationally, COVIDView surveillance indicators tracking levels of SARS-CoV-2 virus circulation and associated illnesses have been increasing since September 2020, reported the US Centers for Disease Control and Prevention (CDC) on October 23, 2020. The rate increased from 5.6% during week #41 to 6.3% during week #42.

This change is driven primarily by activity in the Southeastern and Central parts of the USA.

Furthermore, since the week ending September 26, 2020 (#39), overall weekly hospitalization rates have increased in the USA, driven primarily by an increase in rates among adults aged 50 years and older.

And, based on death certificate data, the percentage of fatalities attributed to pneumonia, influenza, or COVID-19 (PIC) for week 42 was 7.6% and, while declining, remains above the PIC epidemic threshold, stated the CDC.

Oct 23, 2020 • 11:27 am CDT

Serum Institute of India Pvt. Ltd. revealed an agreement with Merck to develop SARS-CoV-2 neutralizing monoclonal antibodies (mAbs) co-invented by IAVI and Scripps Research as innovative interventions to address the COVID-19 pandemic. Neutralizing mAbs against SARS-CoV-2 are widely considered to be promising candidates for COVID-19 treatment and prevention, stated Serum's press release.

This agreement announced on October 22, 2020, 'builds on the advanced antibody discovery and optimization expertise of IAVI and Scripps Research, gained from years of experience in HIV broadly neutralizing antibody research and development, and on Merck’s and Serum Institute’s significant capabilities in design and scale-up of accelerated manufacturing processes for mAb production.'

“I am confident that we and our partners are on a productive path that will lead to a much-needed, globally available tool for COVID-19 treatment and possibly prevention,” added Adar Poonawalla, CEO, Serum Institute.

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Oct 23, 2020 • 11:16 am CDT

A new viewpoint article published by Science states: 'as we learn more about SARS-CoV-2 transmission, important uncertainties remain. The majority of SARS-CoV-2 infections likely occur within households and residential settings such as nursing homes. This is because most individuals live with other people, and household contacts include many forms of close, high-intensity, and long-duration interaction.'

'The relative risk of transmission in different community settings, such as restaurants and retail stores, is still unclear, as is the impact of mitigation measures in these contexts. It is still unknown how seasonality and heterogeneities in the population distribution and duration of immunity will affect future transmission dynamics.'

'Filling these and other knowledge gaps will clarify how the engines of transmission interact to drive the pandemic—and how best to fight back.'

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Oct 22, 2020 • 4:42 pm CDT

Texas Governor Greg Abbott announced that the Texas Department of State Health Services (DSHS) and the Texas Division of Emergency Management are surging additional medical personnel and equipment to the El Paso region to assist with the community's COVID-19 response.

The DSHS is deploying over 460 medical personnel to the region this week, and the agencies are sending a Texas Emergency Medical Task Force ambulance bus, medical incident support team, five ambulances, and mobile medical units to assist first responders. DSHS is also deploying 48 patient monitors, 25 medical beds, and 30 oxygen concentrators to support area hospitals.

Currently, El Paso’s emergency response warehouses are stocked with over 4.8 million masks, over 629,000 gowns and coveralls, over 400,000 gloves, over 38,000 face shields, and additional PPE.

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Oct 22, 2020 • 4:24 pm CDT

California-based Gilead Sciences, Inc. announced that the U.S. FDA approved the antiviral drug Veklury® (remdesivir) for the treatment of patients with COVID-19 requiring hospitalization.

“The approval of Veklury marks an important milestone in efforts to help address the pandemic by offering an effective treatment that helps patients recover faster and, in turn, helps preserve scarce healthcare resources,” said Barry Zingman, MD, Professor of Medicine at the Albert Einstein College of Medicine and Montefiore Medical Center, New York, in a press release.

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Oct 22, 2020 • 2:20 pm CDT

The new, World Health Organization (WHO) approved antigen-based rapid diagnostic tests for the novel SARS-COV-2 coronavirus in Africa will significantly boost testing capacity and marks a game-changer in the continent’s fight against COVID-19, stated the WHO on October 22, 2020.

Rapid antigen tests are an addition to polymerase chain reaction (PCR) tests, not a replacement for them. They are more reliable in patients who are symptomatic, with a high viral load, or a lot of coronavirus in their upper respiratory tract.

Most African countries conduct polymerase chain reaction or PCR tests, the gold standard, which require laboratories, reagents, and experts, limiting COVID-19 testing mostly to large cities. People can wait from 48 hours to more than 10-days for results as they are sent for laboratory verification.

The new rapid tests are easy to use, cheaper than PCR tests, and provide the results in less than 30-minutes, enabling countries to decentralize testing, added the WHO.

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Oct 22, 2020 • 12:13 pm CDT

The U.S. FDA’s Vaccine and Related Biological Products Advisory Committee (VRBPAC) announced around 1 PM EST, during its digital meeting on October 22, 2020, that the VRBPAC is not suggesting mandating COVID-19 vaccinations.

However, the leaders of the VRBPAC are recommending the Vaccinate with Confidence strategic framework as the tactic to strengthen vaccine confidence and prevent outbreaks of vaccine-preventable diseases in the USA.

'Trust in vaccines is not built through a top-down approach but through millions of conversations between parents, doctors, nurses, pharmacists, and community members,' states the Vaccinate with Confidence framework.