Coronavirus Breaking News

The coronavirus disease COVID-19 is currently reaching pandemic levels in various countries.

Apr 9, 2021 • 2:25 pm CDT

Following reports of cases of thromboembolic events in unusual locations, France's Haute Autorite de Sante (HAS) recommended on April 9, 2021, that Vaxzevria, known as AstraZeneca COVID-19 vaccine, be reserved for people over 55 years of age.

Before this HAS restriction, just over 500,000 people under the age of 55 received the first dose of the Vaxzevria - AstraZeneca vaccine in France during 2021.

The HAS states 'as the administration of a single dose of this vaccine is insufficient to guarantee lasting effective protection.

Thus, given the existence of a scientific rationale and encouraging data, the HAS now 'recommends using a dose of one of the mRNA vaccines currently available, Comirnaty or COVID-19 Vaccine Moderna, to replace the administration of the second dose in persons under 55 years of age who have received the first dose of Vaxzevria vaccine.'

The Haute Autorité de Santé website is registered in France with the National Commission for Informatics and Freedoms under number: 615994.

Separately, the European Medicines Agency (EMA) safety committee concluded on April 9, 2021, that unusual blood clots with low blood platelets should be listed as infrequent side effects of Vaxzevria (COVID-19 Vaccine AstraZeneca).

The EMA reminds healthcare professionals and people receiving the vaccine to remain aware of the possibility of blood clots combined with low levels of blood platelets occurring very rarely within 2 weeks of vaccination.

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Apr 9, 2021 • 10:05 am CDT

The U.S. CDC reported about 385 million RT-PCR diagnostic tests had been performed to confirm SARS-CoV-2 coronavirus infections as of late on April 8, 2021.

Recent data published by Statista on April 6, 2021, indicates the USA leads all other counties in COVID-19 tests processed. The USA is followed by India (250m) and China (160m).

As of April 6, 2021, the U.S. Food and Drug Administration (FDA) announced it had authorized 355 coronavirus diagnostic tests, including 258 molecular tests, 75 antibody tests, and 22 antigen tests during the COVID-19 pandemic.

Furthermore, the FDA had authorized 43 molecular tests for home-collected samples.

The FDA recently published A Closer Look at COVID-19 Diagnostic Testing to offer those who might purchase COVID-19 tests more technical information and resources. The COVID-19 tests most people discuss are RT-PCR, the nasal-swab test that detects viral RNA, and various antibody tests that detect if you have an immune response due to past exposure to the SARS-CoV-2 beta coronavirus.

Apr 7, 2021 • 6:03 pm CDT

The Canadian Council of Chief Medical Officers stated on April 7, 2021, 'As we accelerate vaccination in Canada, we understand that everyone is looking forward to returning to a sense of normalcy.'

'We will be able to do this gradually based on local and regional COVID-19 activity, but we need to be careful.'

For example, Toronto Public Health issued a statement on April 6th confirming schools will be shut down as the city reported 955 new cases. The closure means more than 300,000 students, including those who attend private or independent schools, will return to learning from home exclusively.

And Ontario has declared its third province-wide state of emergency, issuing a stay-at-home order effective on April 8th.

'COVID-19 variants of concern are causing a rapid resurgence in Canada and threatening the sacrifices we have made to prevent and control COVID-19. We cannot let our individual and collective guards down until there is sufficient population protection from vaccination.'

'This means that for now, everyone needs to continue with public health measures that we know are effective, regardless of whether you have received one or two doses of vaccine or are not yet vaccinated.'

'As vaccination rolls out across Canada, it provides us with the opportunity to consider how best we can adapt public health measures and gradually lift the most restrictive ones.'

'As Chief Medical Officers of Health, we are committed to reviewing the evidence to inform when and how it is safe to relax these measures. We will continue to work together to provide clear and evidence-informed advice as the science and situation evolve, to keep everyone in Canada safe and healthy.'

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Apr 7, 2021 • 12:01 pm CDT

The U.S. CDC reported on April 7, 2021, among 378,048 death certificates from 2020 listing COVID-19. Among 357,133 death certificates with at least one other medical condition listed, 97% had a co-occurring diagnosis of a plausible chain-of-event condition (e.g., pneumonia or respiratory failure) or a significant contributing condition (e.g., hypertension or diabetes), or both.

Only 5.5% of death certificates identified COVID-19 without other medical conditions listed.

This finding was more frequent for death certificates indicating that the death occurred not in a hospital but in the decedent’s home (38.3%), a nursing home or long-term care facility (38.5%), or a hospice facility (23.2%).

The CDC says this finding was noted for adults aged 18–84 years, both genders, all races and ethnicities, those who died in inpatient and outpatient or emergency department settings, and those whose manner of death was listed as natural.

This study's corresponding author was Adi V. Gundlapalli, agundlapalli@cdc.gov.

Apr 7, 2021 • 7:59 am CDT

The Olympic Flame is scheduled to go through the Osaka prefecture in Japan on April 13, 2021, but Governor Yoshimura said it would be "inappropriate" to hold it on public roads amid fears over large gatherings that could spread the (SARS-COV-2) virus,' reported Kyodo News.

"Today, we asked people in the whole of Osaka to refrain from engaging in unnecessary, non-essential outings," Yoshimura informed Reuters.

The decision to cancel the Olympic event across the Osaka Prefecture came as it confirmed a record 878 additional COVID-19 cases on April 7, 2021.

Toshiro Muto, CEO of the Tokyo Games organizing committee, announced Olympic torchbearers would run at the Expo '70 Commemorative Park in the city of Suita instead of public roads in Osaka.

The US Department of State recently issued a Level 3 Travel Advisory on March 29, 2021, saying 'Reconsider travel to Japan due to COVID-19, as the disease is still a serious concern in Tokyo and across many areas of Japan, and restrictions on entry remain in effect.'

Visit the US Embassy's COVID-19 page for more information on COVID-19 in Japan.

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Apr 6, 2021 • 3:15 pm CDT

Researchers at the Manisa Celal Bayar University (MCBU) Medical Faculty Hospital in the Republic of Turkey completed the first comprehensive, local study of the 'immune response to the SARS CoV-2 Inactive (Sinovac-Coronavac) vaccine.

Between early January and March 18, 2021, researchers ran tests among 1,053 people without SARS-CoV-2 antibodies. All were health care workers who were prioritized in the country’s inoculation campaign.

In a media statement issued on April 5, 2021, the researchers stated, "After the first vaccine, there is not enough immunity, and after the second vaccine, an inactive vaccine boosts immunity to 99%.

Dr. Şebnem Şenlo Akar emphasized that the vaccine has an antibody development rate of 97% in men and 99% in women. "We have created immunity in a large part of the society."

The rate of people suffering from slight side effects like pain in the spot where the vaccine is administered and a headache was below 25%. “Serious side effects were below 1%,” researchers said.

The scientific study on the Sinovac-Coronavac Vaccine' was conducted by the academic staff of the Department of Infectious Diseases, Public Health and Medical Microbiology of Manisa CBU Faculty of Medicine.

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Apr 6, 2021 • 9:45 am CDT

The WHO Regional Director for Africa, Dr. Matshidiso Moeti, issued a statement on World Health Day 2021, calling on everyone to build a fairer, healthier world.

'The COVID-19 pandemic has shone a light on inequalities in African countries that account for around 17% of the global population.

Amid shortages of essential supplies, African countries have been pushed to the back of the queue in accessing COVID-19 test kits, personal protective equipment, and vaccines.

Of 548 million COVID-19 vaccine doses administered worldwide, only 11 million, or 2%, have been in Africa.

At WHO, we are working with countries to strengthen capacities to collect, manage, and use data and enhance monitoring and action to address avoidable inequities. We have disseminated technical guidance on gender, equity, and COVID-19 and trained 30 country teams in the past year. These teams are using skills gained to support equitable health response, including to deal with gender-based violence in the context of COVID-19.'

COVAX, part of the Access to COVID-19 Tools Accelerator, is facilitating equitable access to COVID-19 tests, treatments, and vaccines to address these issues.

COVAX has built a diverse portfolio of vaccines suitable for a range of settings and populations and is on track to meet its goal of delivering at least 2 billion doses of vaccine to participating countries around the globe in 2021, including at least 1.3 billion donor-funded doses to the 92 lower-income COVAX Facility participants.

Apr 5, 2021 • 6:20 pm CDT

The US Centers for Disease Control and Prevention (CDC) issued several Level 4 Travel Alerts regarding the ongoing COVID-19 pandemic. As of April 5, 2021, the CDC's High-Level Alerts state, 'Travelers should avoid all travel to these countries.'

The list of countries includes, but is not limited to, Argentina, Belgium, Bermuda, Brazil, Canada, Costa Rica, France, Greece, and many others.

The CDC stated 'Because of the current situation, even fully vaccinated travelers may be at risk for getting and spreading COVID-19 variants and should avoid all travel to these countries. If you must travel, get fully vaccinated before travel.'

There are three experimental COVID-19 vaccines authorized in the USA, and globally, there are nine other COVID-19 vaccines currently available worldwide.

Furthermore, check with your destination's Office of Foreign Affairs or Ministry of Health or the US Department of State, Bureau of Consular Affairs, Country Information page for details about entry requirements and restrictions for arriving travelers.

Additionally, returning to the USA has new requirements.

All air passengers coming to the USA, including U.S. citizens and fully vaccinated people, are required to have a negative COVID-19 test result in no more than 3 days before travel or documentation of recovery from COVID-19 in the past 3 months before they board a flight to the USA, says the CDC.

And do not travel if you were exposed to COVID-19, you are sick, you test positive for COVID-19, or you are waiting for the results of a COVID-19 test. Moreover, don’t travel with someone who is sick, says the CDC.

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Apr 5, 2021 • 2:51 pm CDT

According to a study published in The Journal of Infectious Diseases on April 2, 2021, 'These results suggest that transmissibility differences among SARS-CoV-2 lineages are likely, not due to differences in aerosol stability.'

The stability in aerosols of four SARS-CoV-2 isolates, including one from lineage B.1.1.7, is similar when compared across multiple environmental conditions. These researchers focused on an isolate of B.1.1.7 as well as three other Coronavirus strains (hCoV-19/France/IDF0372/2020, hCoV-19/USA/NY-PV08449, and hCoV-19/USA/WA-1/2020), testing the effects of light, humidity, and temperature on aerosols from a simulated respiratory tract lining fluid in a rotating drum chamber.

No difference was identified in the absence of sunlight at 20°C or 40°C, but a small significant difference was seen in some aerosols when exposed to sunlight at 20°C and 20% relative humidity.

"There were no differences in the decay constants between isolates in darkness at either 20°C or 40°C, with a mean time for a 90% loss of viral infectivity across all dark conditions of 6.2 hours."

Despite the small difference, these data suggest that the SARS-CoV-2 lineages represented by all four isolates would be rapidly inactivated by natural sunlight in real-world scenarios.

Apr 5, 2021 • 11:14 am CDT

The Russian Direct Investment Fund (RDIF) and New Delhi-based Panacea Biotec, a leading vaccine and pharmaceutical producer in India, announced today a cooperation agreement to produce 100 million doses per year of the Sputnik V vaccine.

The increased production of Sputnik V at Panacea Biotec sites will facilitate the global supply of Sputnik V to international partners of RDIF.

Dr. Rajesh Jain, Managing Director of Panacea Biotec, commented in a press statement, “Panacea Biotec brings decades of vaccine manufacturing and distribution know-how to scale-up Sputnik V supplies. Panacea Biotec will produce Sputnik V in its internationally accredited facilities complying to strict GMP standards and prequalified by WHO.”

Panacea Biotec has a strong track record of supplying more than 10 billion doses of Polio vaccines and over 150 million doses of Innovative fully liquid Vaccines to National Governments, UN Agencies, etc. Panacea Biotec’s vaccine manufacturing facilities are pharmaceutical and sterile cytotoxic injectable facilities and USFDA approved.

Panacea Biotec launched the world’s first fully-liquid Hexavalent vaccine (DTwP-Hib-HepB-IPV), EasySixTM, in 2017.

To date, Sputnik V has been registered in 59 countries globally with a total population of over 1.5 billion people.

The efficacy of Sputnik V is 91.6%, as confirmed by the data published in the Lancet, one of the world's oldest and most respected medical journals. The vaccine is based on a proven and well-studied platform of human adenoviral vectors. It uses two different vectors for the two shots in the course of vaccination, providing immunity with a longer duration than vaccines using the same delivery mechanism for both shots.

Panacea Biotec is an innovation-led biotechnology company that focuses on the discovery, development, and commercialization of prescription medicines primarily, focusing on Vaccines, Diabetes, Transplant, Gastroenterology, and Oncology.

Apr 5, 2021 • 10:06 am CDT

Massachusetts-based Innovation Pharmaceuticals announced an independent Data Monitoring Committee (DMC) completed its interim safety data review in the Company’s randomized, double-blind, placebo-controlled Phase 2 clinical trial of Brilacidin for treatment of moderate-to-severe COVID-19 in hospitalized patients.

Following their review of thirty patients, the DMC recommended increasing the dosing regimen of Brilacidin from 3 days to 5 days of treatment, as intended per the protocol, which the Company has since implemented. Efficacy data was not reviewed by the DMC and remained blinded.

Recruitment for the 5-day treatment regimen has begun.

“We are thrilled with the recommendation of the DMC pertaining to the safety profile of Brilacidin, a drug that has repeatedly been shown in lab studies by virology experts as a top candidate for fighting infectious and resilient coronaviruses, including SARS-CoV-2, the pathogen responsible for COVID-19,” commented Leo Ehrlich, CEO at Innovation Pharmaceuticals, in a related press release.

“There is a sense of urgency to develop novel pan-coronavirus therapeutics for COVID-19, particularly given the growing spread of variants worldwide, including P1 and B.1.1.7, which appear to be contributing to cases of infection cropping up in patients who have already been vaccinated."

"With its unique mechanism of action to directly disrupt the novel coronavirus, we believe Brilacidin possesses potential to address these worrisome reminders that SARS-CoV-2 isn’t going anywhere."

"More broadly, Brilacidin’s antiviral potency also appears to extend beyond coronaviruses to other types of viruses, based on independent ongoing laboratory research, further supporting Brilacidin’s broad-spectrum antiviral potential.”

Innovation Pharma is developing Brilacidin under Fast Track designation from the U.S. Food and Drug Administration. Brilacidin is a Host Defense Protein mimetic representing a new class of drugs with antiviral, anti-inflammatory, and anti-bacterial properties.

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Apr 4, 2021 • 9:43 am CDT

According to the BBC, seven people have died from unusual blood clots in the United Kingdom (UK) after being vaccinated with the experimental AstraZeneca COVID-19 vaccine (Vaxzevria). A spokeswoman for AstraZeneca stated to the BBC, 'Patient safety remains the company's highest priority.'

Additionally, the UK's Medicines and Healthcare Products Regulatory Agency (MHPRA) received 22 reports of cerebral venous sinus thrombosis (CVST) and 8 reports of other thrombosis events with low platelets, out of 18.1 million doses of COVID-19 Vaccine AstraZeneca given by that date.

The MHPRA commented on April 3, 2021, 'the benefits of the AstraZence Covid-19 vaccine continue to outweigh any risk.'

The World Health Organization and the European Medicines Agency (EMA) recently echoed the conclusion as the MHPRA.

On March 2, 2021, AstraZeneca announced it would supply 142 countries as part of the unprecedented effort with COVAX to bring broad and equitable access to the vaccine.

Recently, the EMA confirmed 'Vaxzevria' was the new name for COVID-19 Vaccine AstraZeneca in Europe.

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Apr 3, 2021 • 2:54 pm CDT

Religious leaders and health officials around the Middle East and North Africa declared that receiving a COVID-19 vaccine anytime during Ramadan will not violate the religious obligation, reported JPost on April 1, 2021.

Sheikh Abdul-Latif al-Derian is reported by the AP on April 2, 2021, to say 'the COVID-19 vaccine is administered intramuscular and won’t spoil the fast.'

It is customary for Muslim adults to fast from dawn to dusk and not violate the religious obligation during Ramadan.

Ramadan is currently scheduled from Monday, April 12 to Tuesday, May 11 in 2021.

Ramadan is the ninth month of the Muslim calendar and the holy month of fasting. It begins and ends with the appearance of the crescent moon, which can vary globally. Because the Muslim calendar year is shorter than the Gregorian calendar year, Ramadan begins 10–12 days earlier each year, allowing it to fall in every season throughout a 33-year cycle, stated Britannica.

On March 30, 2021, Atlanta-based 11Alive researched the question 'Do the COVID-19 vaccines in the USA contain animal products?

No, there are no animal products in the Pfizer, Moderna, or Johnson & Johnson COVID-19 vaccines, wrote 11Alive.

The sources for this 11Alive answer are Dr. Aaron Glatt, Rabbi, Epidemiologist, Chair of the Department of Medicine at Mount Sinai South Nassau, and Dr. Nabile Safdar, President of the Islamic Medical Association of North America.

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Apr 2, 2021 • 1:05 pm CDT

The U.S. Centers for Disease Control and Prevention (CDC0 COVID-19 Vaccination Program began December 14, 2021. As of April 1, 2021, the CDC reports about 56 million people, or 16.9% of the U.S. population, have been fully vaccinated with a COVID-19 vaccine.

A new CDC study published on April 2, 2021, shows that COVID-19 vaccines effectively prevent COVID-19 infections and serious COVID-19 illness. Once fully vaccinated, a person’s risk of infection is reduced by up to 90%.

Additionally, the CDC reported positive trends regarding fatalities related to COVID-19.

Except for an increase during late March 2021, overall, COVID-19 related fatalities have decreased for the past 11 weeks.

On March 31st, the 7-day average of daily new fatalities decreased 74% compared to the highest peak on January 13, 2021 (3,379 deaths).

However, as of March 31, 2021, a total of 549,098 COVID-19 related-fatalities have been reported to the CDC during the pandemic, which started in the USA during January 2020.

Globally, data sources indicate about 2.83 million people have died from a COVID-19 diagnosis.

Apr 2, 2021 • 7:13 am CDT

Beijing-based Sinovac Biotech Ltd. announced that the third production line of CoronaVac®, its COVID-19 vaccine, was completed and put into commercial production. Including this new production line, Sinovac’s annual capacity of CoronaVac has reached 2 billion doses.

As of April 1, 2021, over 200 million doses of CoronaVac have been delivered to over 20 countries, including China.

In the capacity expansion process, Sinovac adhered to the most stringent requirements and did not sacrifice quality for speed and expansion. China’s National Medical Products Administration (NMPA) has inspected the new production line in compliance with quality specifications.

The facility and quality management system of CoronaVac has been inspected by China, Brazil, Indonesia, Chile, Singapore, and Saudi Arabia, as well as the World Health Organization. The large-scale production of hundreds of batches of COVID-19 vaccine proved that the vaccine production process is controllable and the quality is reliable.

Sinovac's press statement indicated it 'will continue to promote the production, supply, and various research studies of CoronaVac® to ensure quality and safety, strive to meet the pandemic prevention and control needs, and make positive contributions to the availability affordability of the COVID-19 vaccine on a global basis.'

Thus far, Sinovac’s COVID-19 vaccine received emergency use approval, or conditional marketing authorization, from over 30 countries.

Sinovac Biotech Ltd. is a China-based biopharmaceutical company that focuses on the research, development, manufacturing, and commercialization of vaccines that protect against human infectious diseases.