Serological Tests Can Detect COVID-19 Disease

FDA issued policy enabling early access to certain serological tests
covid-19 depiction
(Coronavirus Today)

The new FDA Commissioner recently said 'serological tests can play a critical role in the fight against COVID-19 disease by helping healthcare professionals to identify individuals who have overcome infection in the past and have developed an immune response.'

However,  Stephen M. Hahn M.D. said in a statement published on April 7, 2020, 'In the early days of an infection when the body’s immune response is still building, antibodies may not be detected. This limits the test’s effectiveness for diagnosing COVID-19 and why it should ... not be used as the sole basis ... to diagnose COVID-19.'

Serological tests can play a critical role in the fight against COVID-19 by helping healthcare professionals to identify individuals who have overcome infection in the past and have developed an immune response. 

In the future, this may potentially be used to help determine, together with other clinical data, that such individuals are no longer susceptible to infection and can return to work. 

In addition, these test results can aid in determining who may donate a part of their blood called convalescent plasma, which may serve as a possible treatment for those who are seriously ill from COVID-19. 

In March, the FDA issued a policy to allow developers of certain serological tests to begin to market or use their tests once they have performed the appropriate evaluation to determine that their tests are accurate and reliable. 

This includes allowing developers to market their tests without prior FDA review if certain conditions outlined in the guidance document are met. 

The FDA issued this policy to allow early patient access to certain serological tests with the understanding that the FDA has not reviewed and authorized them.

The FDA can also authorize tests for COVID-19 under an Emergency Use Authorization (EUA). 

To date, the FDA has authorized one EUA for a serological test that is intended for use by clinical laboratories.

Since the FDA issued the policy, over 70 test developers have notified the agency that they have serological tests available for use. 

However, some firms are falsely claiming that their serological tests are FDA approved or authorized, or falsely claiming that they can diagnose COVID-19. 

The FDA will take appropriate action against firms making false claims or marketing tests that are not accurate and reliable.

The FDA is an agency that protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. 

COVID-19 testing news published by CoronaVirus Today.